Robert Burns Quotes

Recognized as one of the greatest Scottish writers of all time, Robert Burns had a great deal to say. He was born in 1759 and is perhaps the most well-known Scots language poet. However much of his poetry was also written in English, which often included the bluntest of his harsh political commentary. His English writing often included Scottish dialects. He was a charismatic pioneer of the Romantics literary movement. His most famous work is Auld Lang Syne which is sung in many countries at the stroke of Midnight on New Years Eve to help usher in the new year. Burns claims to have transcribed the folk song from an old man whod had the song passed on to him.   Political Robert Burns Quote While Europes eye is fixd on mighty things, The fate of empires and the fall of kings; While quacks of State must each produce his plan, And even children lisp the Rights of Man; Amid this mighty fuss just let me mention, The Rights of Woman merit some attention. Inspirational Quotes Dare to be honest and fear no labor. Firmness in enduring and exertion is a character I always wish to possess. I have always despised the whining yelp of complaint and cowardly resolve. His locked, lettered, braw brass collar, Shewed him the gentleman and scholar. Libertys in every blow! Let us do or die. Mans inhumanity to man makes countless thousands mourn! Nae man can tether time or tide. Nursing her wrath to keep it warm. Prudent, cautious self-control is wisdoms root. Suspense is worse than disappointment. There is no such uncertainty as a sure thing. Nature Quotes The daisys for simplicity and unaffected air. The snowdrop and primrose our woodlands adorn, and violets bathe in the wet o the morn. Companionship Quotes The wide world is all before us - but a world without a friend. To liken them to your auld- warld squad, I must needs say comparisons are odd. Afflictions sons are brothers in distress; A brother to relieve, how exquisite the bliss! Ah, gentle dames! it gars we greet, To think how mony consels sweet, How mony lengthened, sage advices, The husband frae the wife despises. And may you better reck the rede, than ever did th adviser. And there begins a lang digression about the lords o the creation.

Christianity And The Religions Essay - 1376 Words

Christianity and the Religions Essay Man is called to proclaim the gospel of Jesus Christ and show as many people the way to eternal life, as possible. Because we live in a world of philosophical, cultural, and religious diversity, it is imperative that we interact with people from all walks of life. Christian dialogue with others from various religions can be enlightening – solidifying what we believe as followers of Christ. Accepting people with their various faiths allows us as Christians the ability to gain insight into other beliefs, value systems, and the connections between culture and religion – as well as inspiring personal reflection. Calling to Proclaim the Gospel According to the ‘World Council of Churches’ – A worldwide fellowship of 349 churches seeking unity, a common witness and Christian service, â€Å"Greater awareness of religious plurality has heightened the need for improved relations and dialogue among people of different faiths† (World Council of Churches, 2009). Too often religious identities are drawn into conflict and violence. Perhaps we are then engaging in conversation and attempting to understand one another on the basis of ensuring peace. Or, maybe the definition of tolerance has elicited absolute acceptance or fear, and ‘open-mindedness’ in the spirit of spiritual correctness. Our own prejudices regularly influence how we interact with those of other faiths. Christians are as guilty as anyone in avoiding those differentShow MoreRelated Christianity, the True Religion Essay examples1726 Words   |  7 PagesChristianity, the True Religion I was raised Catholic, at the insistance of my parents. After many years of drinking and partying, I got very bored and thought, Is this ALL there is to life?!?! I thought, If there really IS any truth to a life after death, I should at least TRY to find the answer. I started to do some research on science and religion to see if I could come up with any TRUTH about the meaning of life. 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Surface Perfusion Pressure Method Health And Social Care Essay Free Essays

string(167) " isotropically distributed angle between the dispersing vector and the speed, furthermore, a corrected frequence spectrum is obtained as if all vectors were parallel\." The Doppler Effect ( Doppler displacement ) is the alteration in frequence of a moving ridge ( or other periodic component ) for an perceiver traveling comparative to its beginning. It is normally heard when a vehicle sounding a Siren or horn attacks, base on ballss, and recedes from an perceiver. The frequences observed compared to the emitted frequence are: higher frequence for the receiving system during the attack ( called blue switch if we consider light alternatively of the sound ) , equal frequence when at the blink of an eye of passing by, and lower frequence during the recession ( called red displacement if we consider light alternatively of the sound once more ) . We will write a custom essay sample on Surface Perfusion Pressure Method Health And Social Care Essay or any similar topic only for you Order Now The comparative alterations in frequence can be explained as follows: when the beginning of the moving ridges is traveling toward the perceiver, each consecutive moving ridge crest is emitted from a place closer to the perceiver than the old moving ridge. Then each moving ridge takes somewhat less clip to make the perceiver compared to the last moving ridge. Consequently the clip between the reaching of consecutive moving ridge crests at the perceiver diminishes, which leads to an addition of frequence. As we can see in the figure 1 the distance between consecutive moving ridge foreparts is reduced. On the contrary, when the beginning of moving ridges is traveling off from the perceiver, each moving ridge is emitted from a place further from the perceiver than the last moving ridge, so the reaching clip between consecutive moving ridges is increased, it reduces the frequence. As we can see in the figure 1, the distance between consecutive moving ridge foreparts is increased. Figure 1: On the left side of it can be seen that if the beginning is still, an perceiver will merely see the visible radiation with the same wavelength and frequence as it was emitted. However, on the right side it can be seen what happens with a traveling beginning. ( http: //cfcpwork.uchicago.edu/kicp-projects/nsta/2007/sherman/doppler.htm ) should i compose it in mentions? The difference between the ascertained and emitted frequences is straight relative to the velocity of the beginning towards or off from you, giving: ( Eq. 1 ) is the difference between the emitted and observed frequences is the speed of the receiving system relation to the beginning: it is positive when the beginning and the receiving system are traveling towards each other, and negative when they are traveling apart. Laser Doppler Flowmetry Laser Doppler flowmetry ( LDF ) is a non-invasive diagnostic method of mensurating blood flow in tissue. This technique is based on mensurating the Doppler displacement induced by traveling ruddy blood cells ( RBC ) to the enlightening coherent visible radiation as it can be seen in figure 1. Thankss to LDF we can mensurate flux, speed and concentration of the blood cells in motion from the end product of the instrument. These parametric quantities are extracted from the power spectrum of the photocurrent fluctuations produced by reflected light lighting a photodetector. The perfusion measurings can be divided in two types: optical maser Doppler perfusion imagination ( LDPI ) and, laser Doppler perfusion monitoring ( LDPM ) ( 1 ) . In this undertaking LDPM is the method used. Figure 1: the sensing of a ruddy cell flux by optical maser Dopple flowmetry. Laser visible radiation is conducted to the tegument via fibre optics. In the tegument, a little fraction of the visible radiation is reflected by traveling ruddy cells with a shifting frequence ( Doppler consequence ) , whereas the remainder is reflected by the same frequence. Both reflected beams are transmitted to the having optical fibre. ( 2 ) The major advantage of the optical maser Doppler techniques in general is their non-invasiveness and their ability to mensurate the microcirculatory flux of the tissue and fast alterations of perfusion during aggravations. The technique can mensurate perfusion quantitatively ( although relation ) in existent clip. ( 1 ) However, there are some restrictions of the technique: the influence of optical belongingss of the tissues on the perfusion signal, gesture artefact noise, unknowingness of the deepness of measuring, absence of quantitative units for the biological and perfusion zero signal ( at no flow status ) . ( 1 ) Some of them will be farther explained in the undermentioned paragraphs. Light dispersing in tissue Photons are scattered by inactive and dynamic atoms if a beam of optical maser visible radiation illuminates a little country of tissue. Therefore, the traveling RBC/RBCs? ( plural ) impart a Doppler displacement to the photon, what depends on the wavelength, the dispersing angle and the speed vector of the scatterer. Figure 3: Scattering of a photon ( wave vector qi and frequence I†° ) by a traveling RBC ( speed V ) ( reproduced from ( 1 ) ) When a moving ridge with frequence I†° is scattered from a traveling atom with speed V ( figure 3 ) , the Doppler displacement can be written as: ( Eq.2 ) qi is the incident moving ridge vector, Kansas is the wave vector of the scattered moving ridge, and I? is the angle between the speed vector and the sprinkling vector, defined as ( kI-ks ) . If I ± is the dispersing angle and I » the wavelength of the visible radiation in the medium, the Doppler displacement can be written as: ( Eq.3 ) However, there is non merely one alone Doppler displacement measuring. On one manus, in tissue with a big figure of traveling ruddy blood cells, and for sufficiently long photon way lengths, photons undergo more than one Doppler displacement, so, more than one Doppler-shifted frequence is obtained usually. On the other manus, the fact that microcirculatory blood vass have no standard orientation and randomisation of the photons with different dispersing events give rise to a scope of Doppler displacements, even if all the ruddy blood cells move at equal velocity. Hence to obtain an absolute speed measuring one needs to cognize the dispersing angle I ± , the angle between the speed vector and the sprinkling moving ridge vector I? , and the figure of Doppler displacements in the instance of multiple sprinkling. The job is solved theoretically presuming an isotropically distributed angle between the dispersing vector and the speed, furthermore, a corrected frequence spectrum is obtained as if all vectors were parallel. You read "Surface Perfusion Pressure Method Health And Social Care Essay" in category "Essay examples" Finally, the end product spectrum is corrected for assorted waies of speed and besides the mention vector, by generation of the Doppler displacement by the differential coefficient of the spectrum. This last measure leads to a velocity-resolved flow measuring. ( 3 ) Depth sensitiveness The measurement deepness depends chiefly on both biological and optical facets. On one manus, it depends on the tissue belongingss such as the construction and denseness of the capillary beds, temperature, pigmentation, oxygenation, etc.. On the other manus, it depends on the wavelength of the optical maser visible radiation and on the distance between theA sending and receivingA fibres in the optical maser Doppler probe.A Since the optical soaking up by blood and, to a smaller extent, the dispersing degree of the tissue differ significantly for green, ruddy and infrared visible radiation, this may be utilized to mensurate the blood flow in tissue volumes of different size and deepness. ( 1 ) Figure 2: calculated wavelength-dependent incursion deepness of visible radiation into tissue ( blood volume 5 % , oxygenation 80 % , H2O content 80 % , ) over a wavelength scope from 500 nanometers to 100 nanometers ( reproduced from ( 4 ) ) . From figure 2 the wavelength dependance of the incursion deepness of visible radiation into tissue can be seen. Green visible radiation ( 543 nanometer ) has a smaller incursion deepness ( 0.33 millimeter ) into tissue than both ruddy visible radiation ( 633 nanometer ) and infrared visible radiation ( 800 nanometer ) , they penetrate to 3.14 millimeters and to 4.3 millimeters severally. ( 4 ) Another issue is the action of the heat, local heat regulates the tegument blood flow ( SkBF ) . In human existences local heating below hurting esthesis evokes vasodilatation, so addition of blood flow, this is mediated both by neurogenic physiological reactions and locally released substances. These interactions between the nervous mechanisms and local factors are highly complex. ( 5 ) Many factors can act upon on the response, but in general, local warming evokes an initial dilator response that peaks in a few proceedingss, followed by a brief low-water mark, and so a secondary dilation to a tableland that can be sustained. What means that the tegument is known to be innervated by two different parts of the sympathetic nervous system: an sympathomimetic vasoconstrictive system part to resting cutaneal vascular tone and a cholinergic vasodilative system having an unknown neurotransmitter coreleased with acetylcholine. ( 5 ) ( 6 ) Figure X A: representative tracing of the local warmer set temperature and the skin temperature at the local heater-skin surface interface during the local warming protocol. Bacillus: representative tracing of the tegument blood flow ( SkBF ) response to the local warming protocol. Local warming resulted in a bimodal addition in SkBF. Prolonged warming in some topics caused a gradual diminution in SkBF after 50 min. Valuess are expressed as a per centum of maximum SkBF during extract with50 millimeter Na nitroprusside. ( 5 ) As we can see from Figure 1A there are distinguishable responses to the local warming. In human existences the skin temperature is about 30 grades, so, if it is heated until 40 and remained changeless as it is done in ( B ) two responses are clearly seen. The flow before the warming is called baseline flow, after warming, a rapid addition in SkBF is found. After a transeunt bead follows and eventually a secondary progressive rise to a tableland is found. After drawn-out warming ( 50 min ) , SkBF begins to worsen in some, but non all, topics despite the care of an elevated tegument temperature. ( 5 ) I have to associate this to the minuts that I chose for my measurings! ! ! ! ! The last facet to reference is the altering the source-to-detector separation, measurings with a flow theoretical account showed that a larger separation between beginning and sensor increased sensitiveness to deeper flows, whereas a smaller separation between beginning and sensor steps more superficially. ( 7 ) Human tegument is the largest organ of the organic structure and has an mean thickness of 1-2 millimeter. LDF mensurating deepness is in the order of 0.5-1 millimetre. Sing incursion deepness and source-to-detector separation and in order to make this deepness a investigation with standard fibre separation ( 0.25 millimeter ) , and a 780 nm wavelength optical maser are used in this undertaking. ( is it ok if I mention this facet of the undertaking already? ) Furthermore, we have chosen the investigation PROBE 457 ( 357 ) Angled Small Thermostatic Laser Doppler Probe to be able to heat the tissue and therefore, the effects of the temperature can be studied. Calibration Standardization is required in comparing the degree of perfusion in different measurings and from different instruments owing to the fact that the optical maser Doppler perfusion signal is a comparative step of flux. Then, we can look into the instrument ‘s stableness, set up the one-dimensionality of the instrument ‘s response to blood flow, set up relationships between different instruments, and associate the reading of the instrument to existent perfusion ( if it is possible ) . There is no gilded criterion until now available for the standardization of the optical maser Doppler instrument for perfusion measurings. The job is that the distribution of blood vass in tissue and optical belongingss is heterogenous, hence it is hard to graduate an instrument to mensurate absolute blood flow per unit volume of tissue. Even though is non the aimed gold criterion, a simple method has been in usage for frequent and easy standardization of optical maser Doppler instrumentality. It is about an aqueous suspension of polystyrene microspheres in Brownian gesture called a motility criterion. The Doppler displacement generated by the atoms in Brownian gesture is used to graduate the system ‘s overall unity for a comparing of measurings at different clip intervals. In our undertaking the investigations are calibrated sing the Brownian gesture of our atoms equal to 250 perfusion units ( PU ) . In our measurings, since no current optical maser Doppler instrument can supply absolute perfusion values ( e.g. ml/min/100 gram tissue ) measurings will be expressed in as Perfusion Units ( PU ) , which are arbitrary. Calibration is required therefore a particular motility criterion PF100 developed by Perimed is used for this undertaking. Skin Perfusion Pressure ( SPP ) method Skin Perfusion Pressure ( SPP ) is a noninvasive method to mensurate the blood force per unit area of the microcirculatory flow in the tegument at a 1-2mm tegument deepness. SPP measures in millimetres of quicksilver ( mmHg ) the force per unit area at which blood flow foremost returns to the capillaries. Figure X, proctor, turnup and Doppler investigation set-up for SPP. ( I do non like it, I will utilize my exposures ) Skin Perfusion force per unit area is performed by puting a proctor of microcirculation ( in our instance is Laser Doppler investigation ) on the tegument ( see figure X ) , puting a force per unit area turnup on it and blow uping the force per unit area turnup until the microcirculation disappears. Then, the air leaves the force per unit area turnup easy until the microcirculation appears which can be seen by the optical maser Doppler signal on the proctor of the first channel, figure X. Figure Twenty: the microcirculation displacement by the optical maser Doppler can be seen in the first channel, the signal disappears when the force per unit area in the turnup is increased ( impart three ) to barricade the microcirculation at 40 grades, skin temperature by the 2nd channel. When the force per unit area in the turnup decreases, the force per unit area on the tegument returns at one point, the SPP ( T flag ) . The force per unit area in the force per unit area turnup at the clip the microcirculatory flow returns is defined as the SPP at that point of the tegument, on the instep portion of the pes in the instance of figure X. The SPP in mmHg is pointed out in the 3rd channel of figure XX. Even though the best organic structure place on skin perfusion force per unit area in patients with terrible peripheral arterial disease ( see pag X ) is in the sitting place after the pes had been lowered vertically for 10 min, the chief demand is that the height degree of the mensural portion coincides with the degree of the bosom ( 8 ) . The measurings in the undermentioned undertaking are taken at supine place since the voluntaries are healthy and it is a comfy place. SPP value is a mention value that measures the chance of healing of hurts and ulcers related to the force per unit area measured on the tegument every bit good as diagnosings CLI and PAD diseases. There have been several statistical surveies about SPP cut-off value as we can see in table Ten, sum uping the interval between 30-40 mmHg is the critical scope, below ulcers and hurts will now mend, above they will. ( 9 ) ( 10 ) ( 11 ) ( 12 ) ( 13 ) Report Standards Consequence Castronuovo, Adera, Smiell and Price, 1997 lt ; 30 mmHg Command line interface Lo, Sample, Moore and Gold, 2009 lt ; 30 mmHg lesion unlikely to mend A a†°? 30 mmHg lesion probably to mend Yamada, Ohta, Ishibashi, Sugimoto, Iwata, Takahashi and Kawanishi, 2007 lt ; 40 mmHg lesion unlikely to mend and severe PAD A gt ; 40 mmHg lesion probably to mend Adera, James, Castronuovo, Byrne, Deshmukh and Lohr, 1995 lt ; 30 mmHg lesion unlikely to mend A a†°? 30 mmHg lesion probably to mend Table Ten: Reference SPP values for healing and for foretelling CLI and PAD. If the patients suffer of sphacelus, ulcers and/or there is a demand of amputation for other grounds, SPP is a tool to demo with great truth if the hurt would mend or non. A survey shows experimental consequences sing SPP cut-off value when make up one’s minding on amputation when enduring from ulcers ( see figure XXXX ) . Figure XXXX: SPP values for all limbs. Group I patients ( n = 32 ) required vascular Reconstruction or major amputation in the sentiment of vascular go toing sawbones. Group II patients ( n = 29 ) were non thought to necessitate vascular Reconstruction to mend and were managed with local debridement, minor amputation, or both. All foot lesions and amputation lesions in group I healed ( reproduced from ( 10 ) ) Figure XXXXXV: Logistic arrested development analysis of patients ( n=29 ) that were non thought to necessitate vascular Reconstruction to mend and were managed with local debridement, minor amputation, or both correlating a given SPP with chance of mending. ( 10 ) From figure XXXXXV it can be seen that SPP values between 20 and 30 millimeter Hg do non foretell mending with great truth. But an SPP value less than 20 mm Hg and an SPP value greater than 30 mm Hg predict the result of local therapy rather accurately. ( 10 ) SPP is non changeless in all organic structure skin surface, as it can be seen in the tabular array below. SPP is normally lower the further of the bosom, therefore it consequences with a really low value when patients suffer from CLI and PAD. Degree Normal Mean SPP Ischemic mean SPP Brachial 52A ±3 55A ±8 Above Knee 50A ±5 46A ±4 Below Knee 42A ±4 22A ±4 Dorsal pes 43A ±4 10A ±2 Dorsal toe 55A ±5 16A ±4 Plantar toe 73A ±5 17A ±3 Table Thirty: different SPP values in both healthy and ischaemic voluntary limbs ( reproduced from ( 14 ) ) . Applications Falten bibliografiesssssssss Peripheral Arterial Disease ( PAD ) Peripheral vascular disease ( PAD ) is a narrowing of blood vass that restricts blood flow. It largely occurs in the legs, but is sometimes seen in the weaponries. More restrictedly speech production, PAD includes a group of diseases in which blood vass become restricted or blocked. Typically, the patient has peripheral vascular disease from artherosclerosis, which is a disease in which fatty plaques form in the interior walls of blood vass. Blood coagulums are another procedure taking to PAD, which restrict blood flow in the blood vass. In some instances PAD may happen all of a sudden if an intercalation or when a smudge coagulum quickly develops in a blood vas already restricted by an atherosclerotic plaque, and the blood flow is rapidly cut off. Even thoguh venas and arterias can be affected, but the disease is normally arterial, that is why is called PAD. The chief symptom is pain in the affected country. Since this disease is seen chiefly in the legs, the hurting and other symptoms normally occur when walking. The symptoms may vanish when resting. As the disease becomes worse, symptoms occur all the clip, even at remainder. At the most terrible phase of the disease, when the blood flow is greatly restricted, sphacelus can develop in those countries missing blood supply. There are different phases harmonizing to the badness of PAD. These phases were classified by Fontaine and Rutherford, they can be observed in the undermentioned talbesxXX X. Phase I – Asymptomatic. Phase II – Intermittent lameness. This phase takes into history the fact that patients normally have a really changeless distance at which they have pain. Phase IIa – Intermittent lameness after more than 200 metres of hurting free walking. Phase IIb – Intermittent lameness after less than 200 metres of walking Phase III – Rest hurting. Rest hurting is particularly disturbing for patients during the dark. Stave IV – Ischemic ulcers or sphacelus ( which may be dry or humid ) . Table ten: Different Fointaine categorization phases to sort PAD. Phase I – Asymptomatic Phase II – Mild lameness Phase III – Moderate lameness – The distance that delineates mild, moderate and terrible lameness is non specified in the Rutherford categorization, but is mentioned in the Fontaine categorization as 200 metres. Phase IV – Severe lameness Phase V – Rest hurting Phase VI – Ischemic ulceration non transcending ulcer of the figures of the pes Phase VII – Severe ischaemic ulcers or blunt sphacelus Table Twenty: Different Rutherford categorization phases to sort PAD There are several factors that may increase the chance of PAD for case: smoke, diabetes, fleshiness ( a organic structure mass index over 30 ) , high blood force per unit area ( 140/90 millimetres of quicksilver or higher ) , high cholesterin ( entire blood cholesterin over 240 mgs per decilitre, or 6.2 millimoles per litre ) , increasing age ( particularly after making 50 old ages of age ) , high degrees of homocysteine ( a protein constituent that helps construct and keep tissue ) and a household history of peripheral arteria disease, bosom disease or shot. ( 15 ) About the diagnosing, PAD can be diagnosed by comparing blood force per unit areas taken supra and below the point of hurting. The country below the hurting ( downstream from the obstructor ) will hold a much lower or undetectable blood force per unit area reading. There are several techniques to name PAD, the most common used in the infirmaries are Ankle-brachial index ( ABI ) , computed Tomographic Angiography ( CT ) , Magnetic Resonance Angiography ( MRA ) , Doppler and Ultrasound ( Duplex ) imagination, Angiography, and Skin Perfusion Pressure ( SPP ) . I will shortly specify them subsequently on this undertaking. If the individual fumes, it is extremely recommended to halt smoke instantly. Exercise is basic to tret PAD. Infections in the affected country should be treated quickly. Surgery may be required to try to handle clotted blood vass. Sing the last phases, limbs with sphacelus must be amputated to forestall the patient to decease. * 5. Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL et Al. ACC/AHA 2005 guidelines for the direction of patients with peripheral arterial disease ( lower extermity, nephritic, mesenteric, and abdominal aortal ) : executive summary a collaborative study from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interverntions, Society for Vascular Medicine and Biology, Society of Interventional Raidology, and the ACC/AHA Task Force on Practice Guidelines ( Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease ) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation ; National Heart, Lung, and Blood Institute ; Society for Vascular Nursing ; Transatlantic Inter-Society Consensus ; and Vascular Disease Foundation. J Am Coll Cardiol 2006 ; 47:1239-312. WHAT HAPPENS IS IT IS A REFERENCE OF A REFERENCE? ? Critical Limb Ischemia ( CLI ) Critical limb ischaemia is defined as limb hurting happening at remainder, or impending limb loss caused by terrible via media of blood flow to the affected appendage. Although the trademark of peripheral arterial occlusive disease is an unequal blood flow to provide critical O demanded by the limb, critical limb ischaemia ( CLI ) occurs merely after chronic deficiency of blood supply, puting off several pathophysiologic events that finally lead to trophic lesions or rest hurting of the legs, or both. ( 15 ) The international consensus about CLI is the undermentioned: any patient with chronic ischaemic remainder hurting, ulcers, or sphacelus attributable to objectively turn out arterial occlusive disease. ( 16 ) It is to be stated that CLI is non to be confused with acute occlusion of the distal arterial tree, alternatively it is a procedure that occurs in a scope frame of months to old ages and, if left untreated, it leads to limb loss secondary to miss of equal blood flow and oxygenation through the distal appendages. ( 15 ) CLI is a terrible manifestation of PAD, so, the patients would be classified in the more terrible terminals of the Fontaine ( present III-IV ) or Rutherford categorization ( grades V-VII ) , seetables X and XX severally. Figure Ten: SPP method measures the chance of mending related to the force per unit area measured on the tegument every bit good as diagnosings CLI and PAD. ( from Vasamed AB, company, non article, it is merely a powerpoint page of a presentation of a company ) ( can I utilize it? ) SPP can name both CLI and PAD therefore, they can be treated. Which is of high relevancy if we consider the high mortality of these diseases. Alternate methods to SPP In order to name both PAD and CLI several methods can be used, they are the undermentioned: Ankle-brachial index ( ABI ) : A a non-invasive method that compares the blood force per unit area in the pess to the blood force per unit area in the weaponries to find how good the blood is fluxing. Normally the ankle force per unit area is at least 90 per centum of the arm force per unit area, with terrible contracting it may be less than 50 per centum. If an ABI reveals an unnatural ratio between the blood force per unit area of the mortise joint and arm, more testing Is needed before doing a diagnose. Computed Tomographic Angiography ( CT ) : a non-invasive trial that shows the arterias in the venters, legs and pelvic girdle. It is peculiarly utile in patients with pacesetters or stents.A A Magnetic Resonance Angiography ( MRA ) : a non-invasive trial that gives information similar to that of a CT without utilizing X-rays.A Doppler and Ultrasound ( Duplex ) imagination: a non-invasive method that visualizes the arteria with sound moving ridges and measures the blood flow in an arteria to bespeak the presence of a blockage.A A Angiography: ( by and large reserved for usage in concurrence with vascular intervention processs ) an invasive method that consists on inject a contrast agent into the arteria and X raies are taken to demo blood flow, arterias in the legs and any obstructions that may be present. 1ST Part: TEMPERATURE DEPENDENCE OF SPP Question hypertext transfer protocol: //dwb.unl.edu/teacher/nsf/c01/c01links/www.science.mcmaster.ca/biology/4s03/thermoregulation.html RESPONSES TO HEAT: When the organic structure is exposed to heat ( Sun, fire, excessively much vesture ) , body temperature rises. Skin heat receptors and blood convey these alterations to the hypothalamic thermoregulator. The thermoregulator inhibits the sympathomimetic activity of the sympathetic nervous system, which control vasoconstriction and metabolic rate, therefore doing cutaneal vasodilation and cut downing BMR. This causes an addition in heat loss via the tegument and a lessening in heat production in the nucleus. If the heat is sufficiently intense, the cholinergic sympathetic fibres, which innervate perspiration secretory organs release ACh, exciting perspiration. Sweating is the most effectual nonvoluntary heat contending response in adult male. Behavioral responses to heat, such as lassitude, resting or lying down with limbs spread out, decreases heat production and increases heat loss. Wearing loose and light vesture, fanning and imbibing cold drinks besides helps wit h heat loss. 40 grades ( a temperature that opens more capillaries, so it is thought that it could increase the An increment vasodilatation and decrease of BMR can increase the flow, so the Doppler signal would be increased. It is something to be tested but the chief inquiry is if these metabolic alterations will act upon SPP. If the optical maser Doppler would merely increase the signal with no alteration of SPP, it would be an tremendous aid for the doctors to acknowledge the SPP value on the monitored information. This old inquiry is to be tested and discussed carefully. SET-UP PF 472 digital/analog convertor A convertor from linear signal to digital signal will be needed in the 2nd portion of the measurings. It is present even though it is non needed in our first portion. PF 5000 Doppler proctor which includes two PF 5010 Laser Doppler Perfusion Monitoring ( LDPM ) units The PF 5010 LDPM Unit is used for blood perfusion measurings based on optical maser Doppler engineering. Laser Doppler measures the sum, local microvascular flow including capillaries, arteriolas, venulas and shunts. Each unit includes one optical maser Doppler investigation. PF 5020 Temperature unit The PF 5020 Temperature Unit is used toA execute local heat aggravation and/or temperature measurings. The PF 5020 unit has two connections for either thermostatic optical maser Doppler probes and/or temperature measuring detectors. one ( Numberss or letters ) PF 5050 Pressure Unit The PF 5050 Pressure Unit is used to command additive or instant turnup force per unit area deflation. It has been developed to simplify and standardise trials such as Skin Perfusion Pressure ( SPP ) . Computer with Perimed PSW 2,5 package PSW 2,5 package will let to obtain the measurings of the PF 5000 Doppler proctor numerically. Pressure turnups 10 centimeter and 12 centimeters Hokanson A force per unit area turnup is a device that shows the force per unit area in mmHg inside the cuff chamber. The breadth required will depend on the breadth of the mark to be measured. The turnup should be 20 % wider than the mark. In our instance, the mark is the in-between calf. hypertext transfer protocol: //www.deh-inc.com/userfiles/image/SC12D % 20PP.jpg Pressure pump WelchAllyn 2005 A force per unit area pump will pump air into the force per unit area turnup. 457 ( 357 ) Angled Small Thermostatic Laser Doppler Probe Probe 457 is a combined optical maser Doppler and thermostatic investigation used for local heat aggravation while blood perfusion is measured. Its optical fibers are integrated in the het country and therefore the whole tissue country under the investigation will be heated. Its fibre separation is 0.25 millimeter. investigation 457 457 Probe Support A support is required in order to enlarge the country of the investigation therefore avoid tilting and increase contact with the investigation. ( our sentiment until the following experimentsssssssss ) ? ? PF 105-3 double-sided adhesive strips Strips are used for arrested development of the tegument and the investigation PF 1000 Calibration Device Aqueous suspension of polystyrene microspheres in Brownian gesture used for the standardization of the investigations in this undertaking. Photosssss, cameraaaaaaaa Method To get down with, the measuring devices have to be calibrated. The optical maser Doppler investigation is calibrated by a motility criterion obtained from Perimed. Since the signal from PF 5000 Doppler proctor is so sent to the PF 472 digital/analog convertor before making the computing machine, so, laser Doppler signal, temperature and force per unit area have to be calibrated every bit good. It is easy since the Numberss are shown in the proctor, so an easy correlativity can be found. Skin Perfusion force per unit area is performed by puting a proctor of microcirculation ( in our instance is laser Doppler investigation ) on the tegument, in our instance is placed in the in-between calf as it is showed in figure Ten. ( PHOTO ) . In our instance we will antecedently line-up the 457 Probe Support, it is obvious that a support will convey more stableness, avoiding tilting and increasing the contact with the investigation? A? . Furthermore, by a Micrometer? A? a degree of 0.5mm of difference has been found between the standard support and the investigation. Perimed employees have lined it up. Then, the force per unit area turnup is placed on the Doppler investigation 457 which is contained inside the lined-up support, being careful that the turnup has the investigation precisely in the center of the blow uping rectangle as it can be seen in figure X. The following measure is taken when the received signal from the optical maser Doppler investigation is regular and familiar, as it can be seen in figure Ten. When can get down the measuring once we receive a regular signal ( basal? A? ) from the optical maser Doppler investigation, so, the force per unit area turnup is inflated until the microcirculation disappears, see figure X. Figure X The three channels are shown through PSW 2,5 package: Doppler laser signal ( perfusion units, PU ) , temperature signal ( Celsius grades ) , force per unit area of the force per unit area turnup ( mmHg ) . The first channel shows the alteration of the optical maser Doppler from a normal flow signal to a low cubic decimeter flow signal. The 2nd channel shows the changeless temperature of the voluntary, 30,9 Celsius grades. ? grades Celsius? The 3rd channel shows how the force per unit area turnup is inflated to accomplish low flow circulation. Then, around 30 seconds are needed in order to stabilise the circulation, so until we get a regular signal from the optical maser Doppler investigation ; hence a level and humdrum signal is obtained. Consequently, the air can be let out by the force per unit area turnup easy until the microcirculation appears as it can been in figure X, which can be seen by the optical maser Doppler signal on the proctor from figure X. The force per unit area in the force per unit area turnup at the clip the microcirculatory flow returns is defined as the SPP. This modus operandi is repeated three times at skin temperature ( 20-35 ( look at the values obtained! ) degrees Celsius ) Figure X The three channels are shown through PSW 2,5 package: Doppler laser signal ( perfusion units, PU ) , temperature signal ( Celsius grades ) , force per unit area of the force per unit area turnup ( mmHg ) . The first channel shows the alteration of the optical maser Doppler from a low-flow signal to a normal flow signal. The 2nd channel shows the changeless temperature of the voluntary, 30,9 Celsius grades. ? grades Celsius? The 3rd channel shows how the force per unit area turnup is easy deinflated and the SPP is pointed out and the Afterwards, the Doppler investigation is heated until a temperature that brings a vasodilatation response ( addition of optical maser Doppler signal ) without hurting ( B ) ! ! ) , 40 grades Celsius. Even though 15 proceedingss are needed harmonizing to ( KRISTIANNN! ) , around two proceedingss will be considered in order to open a important measure of capillaries since in infirmaries the continuance of the trial plays an of import function when taking the medical method to be used. Then, 3 more measurings with the old modus operandi are taken at this new temperature, 40 grades Celsius. Following, the systolic force per unit area is measured in all the voluntaries merely as a standard cheque. hypertext transfer protocol: //www.aqualyte.com.au/pdf/PHYSIOLOGICAL % 20RESPONSE % 20TO % 20HEAT % 20EXPOSURE.pdf ( non used, but may be needed ) Consequence Here follows the list of the 25 voluntaries, with a sum of 28 battalions of measurings. Measurements in the same voluntaries were taken in different yearss. For each voluntary, as it is explained in the Method, 3 recordings are taken and averaged at Tvolunteer, plus 3 recordings are taken an averaged at T=40 grades C. Volunteers: Name Age Weight Gender Anders 42 86 adult male Anders W. A A adult male Asa 48 55 kvinna Bjorn 51 91 adult male Cia 52 70 kvinna Eva 56 53 kvinna Han dynasties 50 79 adult male Hans-Erik 49 77 adult male Jan 58 86 adult male Kjell 75 85 adult male Kristian Euren 49 88 adult male Kristian Euren 2 49 88 adult male Microphone 48 87 adult male Dent A 36 A 100 adult male Niklas 35 80 adult male Oskar 30 92 adult male Patrik 31 70 adult male Per 42 72 adult male Peyman 38 81 adult male Reyhan 28 A kvinna Reyhan 2 28 A kvinna Sara 33 64 kvinna Susanne 35 54 kvinna Susanne 2 35 54 kvinna Sven 55 73 kvinna Thomas B. 48 63 adult male Thomas C. 36 75 adult male Table: voluntaries ‘s name, age, weight and gender. a ) SPP vs temperature and clip -interesting consequences for our undertaking can be found in the tabular array in the Annex, here? -all the consequences obtained ( Wizard Reports ) can be found in the Annex? The chief goul in this portion of the undertaking is to cipher if the Temperature is a factor that influences the SPP, the influence of clip will be studied at the same clip. During the recordings a somewhat addition of the SPP values at the same temperature was noticed for each measuring. In order to explicate it and to seek to avoid this factor act upon our decisions about the temperature, the difference between the first recorded value and the undermentioned values ( until 6 recordings ) for each measuring has been calculated to get down with. The consequences are plotted on figure Ten. Figure X: Pressure difference between the first value in each measuring, and the undermentioned ( until six ) , in each measuring. With a sum of 26 measurings. In order to do the consequences and farther decisions of the graph X more clear, an norm of the differences between the first recordings and the remainder of the recordings for all the 26 considered measuring is calculated and used for farther computations in table Ten. average value difference between the 1st recording and the 2nd ( Tvolunteer ) 4,75 mmHg average value difference between the 1st recording and the 3rd ( Tvolunteer ) 6,15 mmHg average value difference between the 1st recording and the 4th ( T=40 d C ) 9,56 mmHg average value difference between the 1st recording and the 5th ( T=40 d C ) 9,15 mmHg average value difference between the 1st recording and the 6th ( T=40 d C ) 11,15 mmHg Table Ten: average value differences between the 1st and the remainder recordings in each voluntary. From the table Ten we can see that all values of SPP addition on clip and non merely between the 3rd and 4th recordingS, when the temperature is increased till 40 grades. The biggest difference is between the 1st and the 2nd. Just to do certain that it is non an mean artefact, it is deliberate how would alter the deficiency of the first measuring on the overall consequence at Tvolunteer, without warming, see figure XX. Figure Twenty: average values at Tvolunteer, sing merely the 2nd and the 3rd recorded values in each measuring vs sing all three Tvolunteer values obtained. Decision: the 1st value could be excluded. After ciphering the influence of the clip on the recordings and in order to analyze the influence of the temperature on the SPP consequences, the undermentioned consequences will be considered both excepting the first recordings for each measuring, and without excepting them. 156 recordings realized and averaged. 78 averaged values used for farther computations. A Bacillus C 1ST, 2ND, 3d averaged entering values. Tvolunteer 4TH, 5TH and 6TH averaged entering values. T=40 degrees Celsius 2ND, 3RD averaged entering values. Tvolunteer 62,2 68,0667 64,5 60,6 63,2 61,55 38 47,7667 38,8 906 96,8667 88,15 783 95,55 88,15 57,8 68,7333 62,4 532 61,9333 56,8 508 57,3667 54,35 57,6 61,8333 59,7 56,7 55 55,8 81,4 87,2333 82,05 42,8 55,3333 38,4 59,8 59,1333 60,15 61,5 69,6667 61,25 43,0 51,8667 47,3 70,7 77,5333 72,4 77,3 75,25 77,55 58,6 64,4667 57,85 53,6 59,0333 55,8 523 56,3 54,65 60,5 63,3667 60,3 36,1 48,8667 39,5 44,3 47,4 46,2 73,0 82 77,1 69,1 75,3 73,75 90,9 95,8333 93,35 table ten: averaged values in each voluntary depending on the temperature recorded, A at Tvolunteeer. B at T=40. C, at Tvolunteer excepting the 1st recording. The first chief consequence from this first portion will ensue from deducting B-A and averaging the ensuing vector. The 2nd, from deducting C-B. Thus an overall position of the influence temperature can be understood. B-A=6,32 mmHg average value of the averaged T=40degrees-values, subtracted from all six Tvolunteer-values. C-A= 4,5 mmHg average value of the averaged T=40degrees-values, subtracted from the Tvolunteer-values ( excepting the 1st recorded value ) . B ) Baseline V T and clip ( baseline? Stabile phase? ; how could I explicate that? ) In this portion the baseline of both laser Doppler signal ( PU ) and from the turnup ( mmHg ) are studied. Just before pumping both a stable optical maser and force per unit area signal are wanted. Once pumped, after few seconds ( even though 30 sec have been considered in instance ) both signals are stable once more. We have seen that the SPP value is lightly increasing along the recording. The inquiry is if baseline is increasing every bit good or if it is changeless along the measuring, along the recording of the 6 SPP values ( the 3 first recordings at Tvolunteeer, and the 3 following recordings at T=40 grades C ) . First, the optical maser Doppler signal received is studied. The signal should be expected to be higher when the temperature is increased in the tegument surface, accordingly, the alterations of flow can be more ascertained and therefore the obtainance of SPP is simpler. Merely the 10 first measurings are taken into history for the computations. We will analyze it during Tvolunteer and T=40 grades Celsius. From the tabular array X ( ANNEX ) , we can see the consequences of PU in each of the stairss, extracted from the â€Å" Wizard studies † : Tvolunteer A A A A A A A A A A A T=40 grades C A A A A A A A 1st pumping 1st stabilisation 2nd pumping 2nd stabilisation A 3th pumping 3th stabilisation 4th pumping 4th stabilisations 5th pumping 5th stabilisations 6th pumping Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium mmHg Plutonium 7,94 117,29 17,58 0,06 4,67 124,93 19,82 0 4,84 132,99 100,93 0 6,18 137,94 46,74 0 6,21 130,85 49,31 0 6,98 5,74 148,17 14,14 1,35 6,03 146,75 14,61 0,03 6,58 139,49 38,12 0 6,8 139,44 32,49 0 6,65 154,31 25,15 0 6,43 4,85 144,22 14,65 2,94 5,31 153,1 12,48 0,94 5,21 135,74 30,76 0 5,41 146,66 27,65 0,21 5,21 141,12 30,27 0,3 5,34 5,01 137,77 23,79 0,43 4,91 133,32 24,12 0,4 5,1 140,34 33,16 0 5,36 129,5 26,6 0,48 5,2 132,77 28,5 0,5 5,24 2,86 145,89 15,62 0,84 3,19 138,54 11,93 0 3,27 139,53 34,66 0 3,58 148,84 27,68 0 3,63 149,15 29,23 0,39 3,65 5,01 137,77 23,79 0,43 4,91 133,32 24,12 0,4 5,1 140,34 33,16 0 5,36 129,5 26,6 0,48 5,2 132,77 28,5 0,5 5,24 5,2 147,06 17,32 0,47 4,97 154,36 17,05 1,06 4,94 138,69 45,79 0,01 5,34 147,44 40,16 1,29 5,75 128,04 45,72 1,43 5,95 5,51 142,98 21,32 1,09 6,57 136,24 18,15 1,24 5,76 145,81 58,47 0 5,68 141,28 37,53 1,78 5,49 137,24 34,87 1,16 5,87 6,67 151,08 11,93 1,46 6,36 138,32 11,33 0,25 6,02 129,92 36,08 0 6,71 135,67 29,24 0,5 6,37 143,39 41,29 0 6,65 5,6 116,37 18,12 0,38 6,12 123,72 20,55 0,2 5,36 139,05 15,56 0,4 4,45 121,43 21,44 0,87 4,39 118,44 19,94 0,51 4,27 Table X ( possibly let ‘s set in the extension? ) To mensurate the stableness during pumping and non-pumped, the wired norm for each measure is calculated for all 10 measurings, at Tvolunteer: A=2ND PU pumped value -1st PU pumped value B=3th PU pumped value 1st PU pumped value At T=40 grades C: C=4th PU pumped value -1st PU pumped value D=5th PU pumped value -1st PU pumped value E=6th PU pumped value -1st PU pumped value Now, averaging each vector obtained: A -0,135 Bacillus -0,221 C 0,048 Calciferol -0,029 Tocopherol 0,123 Table Ten: mean values of laser signal of all the stabile stairss for all the voluntaries in the pumped stabile phase. It can be seen from table Ten that neither the addition on temperature nor the development on clip are relevant on the PU signal while pumped ( occlusion ) . Then, no farther computations will be taken. Now we consider the measurings of PU on the stabile period before and after the pumping of the turnup, were the first measuring is after the first pumping. At Tvolunteer: F=2ND PU stabile value -1st PU stabile value G=3th PU stabile value – 1st PU stabile value At T=40 grades C: H=4th PU stabile value -1st PU stabile value I=5th PU stabile value -1st PU stabile value As expected from ( bibliographty? ? ? A? ) the addition of T leads to a better signal PU as can be seen in G, H, I vectors. Now, averaging each vector obtained: F -0,41 Gram 24,843 Hydrogen 13,787 I 15,452 Table Ten: mean values of laser signal of all the stabile stairss for all the voluntaries in the unpumped stabile phase. As expected from ( bibliographty? ? ? A? ) the addition of T leads to a better signal PU as can be seen in G, H, I averaged vectors. To complete with this portion the force per unit area ( mmHg ) is studied. Again, merely before pumping a stable force per unit area signal from the turnup is wanted. The inquiry is if this stableness is changeless along the measuring, along the recording of the 6 SPP values. Merely the 10 first measurings are taken into history for the computations. We will analyze it during Tvolunteer and T=40 grades Celsius. If now we consider the measurings of force per unit area on the stabile period before and after the pumping of the turnup, were the first measuring is after the first pumping. At Tvolunteer: FF=2ND force per unit area stabile value -1st force per unit area stabile value GG=3th force per unit area stabile value – 1st force per unit area stabile value At T=40 grades C: HH=4th force per unit area stabile value -1st force per unit area stabile value II=5th force per unit area stabile value -1st force per unit area stabile value It can be seen that neither the temperature nor the clip influence on the force per unit area. Now, averaging each vector obtained: FF -0.4930 GG -0.9040 HH -0.3840 Two -0.4660 Table Ten: mean values of force per unit area of all the stabile stairss for all the voluntaries in the unpumped stabile phase. Discussion 2nd Part: Pressure CORRELATION BETWEEN CUFF AND PROBE ON LIMB PROTOTYPE Question The chief job is that when we measure the air force per unit area in the force per unit area turnup, this force per unit area has been assumed to correlate to the force per unit area applied by the investigation to the tegument. However, this is an indirect measuring that has ne’er been decently evaluated until now. To give an illustration of how unsure is the premise of correlativity between the force per unit area in the turnup and the force per unit area applied by the investigation to the tegument: if the force per unit area turnup is attached really tight on top of the investigation, the turnup will definitively do a force per unit area onto the investigation and accordingly, onto the tegument ; however, the air force per unit area will demo still 0mmHg. To get down with a simple mark, this correlativity is to be tested on limb paradigms, different diameters of tubings folded with different breadths and hardness of froths. Furthermore, there are several constructs unknown: the optimum size of the investigation, the optimum arrangement of the turnup and the investigation, the optimum testing tissue and the optimum methodological analysis of acquiring consequences. In this portion we the investigation size, the investigation and turnup arrangement and the â€Å" tissue † ( represented by a froth hardness and breadth ) are tested. SET-UP PF 472 digital/analog convertor A convertor from linear signal to digital signal, to change over the signal from the force per unit area detector into digital signal sent to Perimed PSW 2,5 package. PF 5000 Doppler proctor which includes two PF 5010 Laser Doppler Perfusion Monitoring ( LDPM ) units The PF 5010 LDPM Unit is used for blood perfusion measurings based on optical maser Doppler engineering. Laser Doppler measures the sum, local microvascular flow including capillaries, arteriolas, venulas and shunts. Each unit includes one optical maser Doppler investigation. PF 5020 Temperature unit The PF 5020 Temperature Unit is used toA execute local heat aggravation and/or temperature measurings. The PF 5020 unit has two connections for either thermostatic optical maser Doppler probes and/or temperature measuring detectors. one ( Numberss or letters ) PF 5050 Pressure Unit The PF 5050 Pressure Unit is used to command additive or instant turnup force per unit area deflation. It has been developed to simplify and standardise trials such as Skin Perfusion Pressure ( SPP ) . Computer with Perimed PSW 2,5 package PSW 2,5 package will let to obtain the measurings of the PF 5000 Doppler proctor numerically. 8 A201 FlexiForce force detectors Sensitive force detectors are needed in order to correlate the mechanical force per unit area of the turnup and of the investigation. SC10 and SC20 Hokanson force per unit area turnups ( 10 centimeter and 12 centimeter ) A force per unit area turnup is a device that shows the force per unit area in mmHg inside the cuff chamber. The breadth required will depend on the breadth of the mark to be measured. The turnup should be 20 % wider than the mark. In our instance, the mark is the in-between calf. hypertext transfer protocol: //www.deh-inc.com/userfiles/image/SC12D % 20PP.jpg UPC2.5 Hokanson force per unit area turnup ( 2.5 centimeter ) A force per unit area turnup of 2.5 centimeter of breadth, which will needed for the smallest tubing ( Xcm diameter ) . Pressure pump WelchAllyn 2005 A force per unit area pump will pump air into the force per unit area turnup. Two 457 ( 357 ) Angled Small Thermostatic Laser Doppler Probe Probe 457 is a combined optical maser Doppler and thermostatic investigation used for local heat aggravation while blood perfusion is measured. Its optical fibers are integrated in the het country and therefore the whole tissue country under the investigation will be heated. Its fibre separation is 0.25 millimeter. investigation 457 457 Probe Support A support is required in order to enlarge the country of the investigation therefore avoiding leaning and increasing contact with the investigation. ( our sentiment until the following experimentsssssssss ) ? ? 457 Probe Support ( lined-up ) A support is required in order to enlarge the country of the investigation therefore avoiding leaning and increasing contact with the investigation. ( our sentiment until the following experimentsssssssss ) . Since it was tested that the bottom portion of the support was 0.5mm deeper in tallness than the investigation, a lining-up has been realized in order to prove the consequence of this difference on the consequences. Probe 457 Silicone Support A more flexible support than the Probe 457 Support will be tested. PF 105-3 double-sided adhesive strips Strips are used for arrested development of the tegument and the investigation Ten, 5cm and 10.5 centimeter diameter tubings Hard plastic tubings that are used as a limb paradigm. 1mm, 5mm, 2cm soft froth and 1.5cm, 2.5cm difficult froth The thickness and hardness of the different froths will play the tissue function around the tubings. Robin goodfellows, peacesaˆÂ ¦ . PHOTO Limb paradigm, tubing of 10cm of diameter ) Photograph Method Conditioning and standardization of the detector The detector Flexiforce is constructed of two beds of substrate composed of polyester movie. On each bed a conductive stuff ( Ag ) is applied, followed by a bed of pressure-sensitive ink. When force applied the electric resistance of Ag diminishes ( the conductance additions ) . Since the electric resistance is reciprocally relative to coerce, the force value can be obtained. After having the detectors the first measure to develop was to mount the electronic box, aid from one expert in electronics was needed from Perimed. The first measure before get downing the measurings is to condition the detector every bit good as understanding how it works. Unfortunately it has been clip demanding to carry through both stages. Here it is the detector ‘s electronic box set-up, where the V entire power has been changed from -1 V to -0.165 V to avoid impregnation of the electromotive force, hence, higher force end product values where obtained. Figure ten: recommended and innitial circuit of the Flexiforce detector. After the first group of measurings, the V T power has been changed from -1V to -0.165 V to avoid impregnation. About the conditioning, the User Manual have been followed exhaustively. The undermentioned stairss have been required to condition the detector: Design of 2 Pucks, little force concentrators and one for each side of the feeling country, to guarantee that all the force travels through the sensing country. It was necessary since the contact country of the burden was excessively big for the sensing country, which has 9.53 millimeter of diameter, see figure X. Perimed manufactured the Pucks. Double-side spines were used to repair the feeling country with the Pucks. Figure ten: Flexiforce sensor A-201. It has a thickness of 0.208mm, length of 197mm and feeling country of 9.53 millimeters diameter. It was recommended to put 110 % ( or more ) of the maximal trial burden onto the detector for about 3 seconds, reiterating in the process 5 times. However, since the highest trial burden was unknown at the beginning, the first 5 detectors have non been conditioned decently. The initial burden trial to status was around 50 N. The remainder of the detectors have been conditioned at around 70 N. Once the detector is conditioned, a standardization is required. In order to make that two stairss were required. It was suggested to put 1/3, 2/3 and the full trial weight on the detector, and mensurating during the timeframe to be used during the existent measurings. Since the full trial weight was still unknown at the beginning, 4 different weights ( 50g, 110g, 300g and 700g ) were used in order to obtain the additive relation between the input value and the end product value. The timeframe was considered to be 30 sec. It was tough to happen quotable consequences. Once the additive arrested development was found, the values were calibrated in the plan sing the weight of the objects, so the existent theoretical force of the objects used to be weighted. Initial jobs of the detector Using 110g weight objects it was troublesome to acquire quotable measurings. Then, farther double-side spines started to be used between the Pucks and the upper and lower objects. Furthermore, the consequences turned to be more quotable when the weight was situated precisely at the same topographic point in every measuring thanks to two perpendicular walls that supported a horizontal card, that contained boundaries that fitted with the cylinder form of the weight. Unfortunately the detector was found to be excessively sensitive, any somewhat weight difference in lading along the lading country brought different consequences. Linearity ( Error ) +/- 3 % Repeatability +/- 2.5 % of full graduated table ( conditioned detector, 80 % force applied ) Hysteresis lt ; 4.5 % of full graduated table ( conditioned detector, 80 % force applied ) Drift lt ; 5 % per logarithmic clip graduated table ( changeless burden of 90 % detector evaluation ) Response Time lt ; 5 microseconds Output Change/Degree F Up to 0.2 % ( ~0.36 % / A °C ) . Loads lt ; 10 pound, runing temperature can be increased to 165A °F ( 74A °C ) . Table ten: different detector belongingss. From the tabular array X it can be seen that the force detector has several issues that could take to non-valid consequences. The one-dimensionality mistake is thought to be overcome it by mensurating many times the same value. The hysteresis is checked by utilizing two weights ( 100g, 300g ) and mensurating while puting the first one, puting the 2nd one, and taking and puting the 2nd object while maintaining the first. No farther surveies were done about impetus. Response clip was measured thanks to a force per unit area turnup and it was established to be around 1 sec. Finally, about temperature influence, the room has been kept all the clip between 23 and 25 grades Celsius. The first measurings Initially 4 parametric quantities have been studied: breadth of the low contact country of the support with the limb, tallness of the support, surface country of the upper contact country of the support with the force per unit area turnup and hardness of the surface of the limb. Alternatively of a human limb, a cylinder of 10cm of diameter and 60cm long has been used with two different hardness froths in each terminal, difficult ( white ) and soft ( Grey ) , figure ten. ( exposure ) . The first measurings were performed with the detector on the surface of the limb, below the investigation support and on top, the turnup environing the limb, see figure X. However, the Pucks moved from the halfway portion of the detector country, the tortuosity and non-vertical forces from the turnup moved the support. So there was low repeatability of the first measurings owing to both high sensitiveness and the instability of the base of the support on top of the limb. The first chief job to work out was instability, the detector was situated on top of the support alternatively, so higher surface was being stack on the limb. On top of the detector a stabilising piece was designed, figure X, in order to avoid non-vertical forces from the force per unit area turnup. Furthermore, tape was carefully set to repair all the objects on top of the protolimb. Consequently the repeatability increased well and since all the interior set-up was more stable, the high sensitiveness was non a job. In order to analyze the parametric quantities different pieces were designed, the farther manufacturation was carried by Perimed. In the tabular array below X all the different pieces are list. WIDTH A ; HEIGHT ( short cylinders ) UPPER CONTACT AREA ( semicylinders ) Hardness 4cm diameter * 1.5cm tallness 10.3cm radius. 1cm height * 11.3cm lenght 1.3cm midst froth 4cm diameter * 0.85cm tallness 4cm radius. 1cm height * 15cm lenght 0.3cm midst froth 5cm diameter * 1.5cm tallness 4cm radius. 1cm height * 3.2cm lenght 5cm diameter * 0.85cm tallness 2.5cm diameter * 1.5cm tallness 2.5cm diameter * 0.85cm tallness Table Ten: all the pieces designed for farther trials. Since the detector is truly sensitive to temperature and fragile ( it brakes if the feeling country is somewhat folded ) a weight of 110g is used to look into if it is decently calibrated and if it works before each measuring. It is to be mentioned that the spines to repair all the objects on top of each other, and specially for repairing the Pucks on the feeling country brought two chief effects: the advantageous effect is that the objects moved from each other when there were high tortuosity or horizontal forces, which meant that the set-up with the force per unit area turnup had to be improved, merely perpendicular forces were aimed. The drawback is that because of the moving of the objects, the spines moved and they had to be replaced, which lead to 5 broken detectors. In order to pump the force per unit area cuff a manual force per unit area turnup was used at first half of the measurings until and automatic and more precise turnup was found in the company. That allowed to decrease the figure of perennial measurings. With the manual turnup, 20 measurings were considered to be necessary for each force per unit area value from the force per unit area turnup: 100mmHg, 75mmHg and 50mmHg in the bulk of the instances. The procedure got less boring and faster when utilizing the automatic force per unit area turnup, so, merely 4 measurings were carried for each value. The 100mmHg value was ever the get downing value, since it is a considerable high force per unit area the interior set-up can be moved. By get downing with this value we avoid mensurating the 40 other values ( 20 per 50mmHg and 20 per 75mmHg ) in vain. The 2nd job found on the manner of the measurings was that with the electronic circuit the values got saturated at 20mmHg. Therefore the V entire end product was changed from -1 V to -0.156 V to acquire lower electric resistance by the detector, in other words, to acquire higher values of force. Now the impregnation degre How to cite Surface Perfusion Pressure Method Health And Social Care Essay, Essay examples

Importance of Legitimation-Free-Samples for Students-Myassignment

Question: Discuss about the Importance of Legitimation. Answer: Introduction The concept of legitimacy is related to the important legal, political and ethical aspects of the research based on the world affairs. Legitimacy is able to present the problem which the research is not able to present due to the vagueness. Political legitimacy is defined as the division between enforcing of the principles on others who are subjected to these. The various types of the liberal democracy related to the practice associated to the political representation. The main objective of the essay is to present the conceptualization of public policy and the various types of the policy approaches related to the same. It has been further able to state why theory of legitimating is important in the first place and the some of the crucial deficit and crisis related to the same. The study will also put forward the strategies and tools legitimating of the events. The essay has been mainly divided into three sections, the first part has been able to introduce the topic, the second part h as been able to bring forward the main argument presented in the topic and the last part of the study has been able to state on the aims of the essay which needs to be achieved (ONeil Ucbasaran, 2016). Main Arguments Public Policy is defined as the principle guide to the action which has been taken based on the action by the various types of the administrative branches of the state in a certain way which is identified to be consistent with the institutional customs and law. The basic foundation of the public policy consists of the different types of the national constitutional laws and the regulations. Some of the other form of the subtractes has been seen with the considerations of both judicial interpretations and the regulations authorized by the regulation (Shirley, 2015). Legitimating of power as per the relevant casual driver in the explaining the policy change and public policy which would not have been possible in the previous two decades. Legitimacy has been historically considered with the top subject of the study related to the political science. The various types of the public policy studies and the research, legitimacy is considered as the the belief in the existing legitimation of power. The traditional political science regimes are seen to relevant to the topic of the study. The various types of the political science are considered as the regimes with the study of legitimacy. Public Policies are considered as simple products which are considered as larger political system, which is seen to be dependent on the broader regime or the legitimacy of the political system (Kailitz, 2013). Legitimacy is important with the power relations. Without the presence of legitimacy, power is exerted with the coercion with legitimacy, and the power can be exerted with the legitimacy power and the power which can be depicted with the voluntary and quasi-voluntary compliance. This power has been seen to be true for armed by the non-state groups. The overall understanding of the legitimacy is considered as an acceptance of the authority which has been evident among the authority of both the elite and the non-elite groups. Legitimacy is seen to be prevalent among the main state-citizen which is seen to be in relation with the whole state building agenda. Legitimacy is seen to be important for forming of the basic foundation of the Government which has seen to be evolved from the support of the public and identified as the only source of the Government. Legitimacy has been further seen to be an integral part of all the regimes and provides the reason for the existence of the regime f or their existence in the first place. The conceptualization of legitimation crisis refers to the decreasing the confidence of the administrative functions, leaderships and the different types of the intuitions for the same. The main initiation of the term was seen to be coined in the year 1973 by Jrgen Habermas. Habermas has been further seen to expand the concept of legtimation crisis with the institution or the organization which do not have the administrative capacity for maintaining effective structures for achieving goals. Legitimation crisis does not involve any unanimity with the social scientists. The usual way of measuring the legitimation crisis needs to consider the different types of the attitudes which have been aimed at the organisation in question (Voronov et al., 2013). In situations where the concept of legitimacy is not seen to be present the negative consequence of power will be more prevalent. In case situations of low amount of legitimacy, this implies that the states are not up to the mark in terms of the delivering the required amount of the various types of the services which are seen to be important for the purpose of public service and further allow the citizens and the rulers will be able to claim for the obedience. The lack of legitimacy will further lead to more domination, resistance, struggle and the instances of interests are less common. The main consideration of legitimacy will lead to explicit testing and the relationship of the various types of the other explanations. The lack of legitimacy will lead to less stable, less war prone and a richer condition for an organization. The main form of the question has been identified with the consideration of legitimacy which is beyond the moral approbation (Bexell, 2014). Legitmation is not seen to be playing an important role in several situations where the political subsystems of the social world are seen to require the input from the mass loyalty. The rationality crisis situation has been also seen to be the situations where the need for legitimating crisis has not seen to be applicable. Some of the various types of the other considerations in absence of the legitimacy have been defined with the various types of the propositions which has been seen to be directly related to the absence of the normative structure and the extent to which the motivation crisis is seen to be prevalent in nature. In some of the various types of the special cases technical and the political aspects of the legitimacy may in a perfect equilibrium and henceforth in such situations the importance of legitimacy may not be experienced (Lafi Josserand, 2016). The main form of the legitimation methods and strategies are seen with policies which are seen to design and configure the power relation which may influence the policy change. As per the social construction the various types of the public policy are seen to be designed with complex set of instrumental and subjective dimensions. Another strategy may be taken in form of various types of the alterations made in the legitimacy pattern (Mackay, 2015). Some of the examples associated to legitimation of events are discussed below: In a study conducted for legitimation of the events of U.S. army withdrawal from Iraq, the main discursive structures included authorization, rationalization, and moral evaluation. This has been seen with linguistic legitimation (Ali et al., 2016). The legitimation strategy to represent the positive aspects of Egyptian revolution and negative repercussion of Hosni Mubaraks regime depicted four main categories of ''authorization'', ''evaluation'', ''rationalization'', and ''mythopoesis''. The study further depicted Far News has been able to put more focus on legitimizing Egyptian revolution rather than delegitimizing Hosni Mubarak's regime. Another aspect of "personal authority" was seen to be more prominent in nature (Academypublication.com, 2017). A study of legitimation on the comparative study in democratic theory and empirical analyses has been able to comply with the challenges in non-democratic regimes (Ecpr.eu, 2017). Another example of the legitimation has been identified with the key process, which has been including the legitimation the strategies and judgements. The main analysis has been depiced with sender-receiver model which has been able to focus on central role of media in the contemporary society. The political developments in South Asia have been identified with specific legitimation strategies. The study has been able to focus on the question of political, moral, and religious forms of leadership in the region and the global South Asian situation. The study depicted that legitimation has led to acceptance and exercising leadership along with authority (Crassh.cam.ac.uk, 2015). The main challenge associated to legitimation may be as a result of difference in the opinion and conflict of the institutions to introduce and establish the various types of the democratic practice. The legitimation crisis has been further viewed as a challenge for the public service. The formation and the expansion of the modern public service have been seen with imitative reproduction in the postcolonial societies continuing for centuries. The disparity in the public onion has been identified as the main challenge in the legitimation process. Along with the public opinion democracy among the public has been also viewed as another problem associated to democracy. In several cases Government has been seen to be lacking the distrust among governing in an age of trust and lacks legitimacy in general. People have been seen to like social security as a result of ligitimation however, in several cases Government has been seen to confiscate the money from the pay check and retire in decad es (Goddard Krebs, 2015). Conclusion The study has been able to state that Public Policy has been defined as the principle guide to the action which has been taken based on the action by the various types of the administrative branches of the state in a certain way which is identified to be consistent with the institutional customs and law. Legitimacy has been historically considered with the top subject of the study related to the political science. The traditional political science regimes are seen to be relevant to the topic of the study. Legitmation is not seen to be playing an important role in several situations where the political subsystems of the social world are seen to require the input from the mass loyalty. Legitimacy is important with the power relations References Academypublication.com. (2017). [online] Available at: https://www.academypublication.com/issues/past/jltr/vol04/05/20.pdf [Accessed 7 Oct. 2017]. Ali, M., Christopher, A. and Nordin, M. (2016). Linguistic Legitimation of Political Events in Newspaper Discourse.Advances in Language and Literary Studies, [online] 7(4), pp.76-83. Available at: https://www.journals.aiac.org.au/index.php/alls/article/view/2402 [Accessed 7 Oct. 2017]. Bexell, M. (2014). Global Governance, Legitimacy and (De)Legitimation. Globalizations, 11(3), 289299. https://doi.org/10.1080/14747731.2014.919744 Crassh.cam.ac.uk. (2015).Leadership, Authority and Legitimation in South Asia CRASSH. [online] Available at: https://www.crassh.cam.ac.uk/events/26168 [Accessed 7 Oct. 2017]. Ecpr.eu. (2017).Legitimation in Non-Democracies: Concepts, Theories and Empirical Evidence across Regime Subtypes. [online] Available at: https://ecpr.eu/Events/PanelDetails.aspx?PanelID=3990EventID=101 [Accessed 7 Oct. 2017]. Goddard, S. E., Krebs, R. R. (2015). Rhetoric, legitimation, and grand strategy. Security Studies, 24(1), 536. https://doi.org/10.1080/09636412.2014.1001198 Kailitz, S. (2013). Classifying political regimes revisited: Legitimation and durability. Democratization, 20(1), 3960. https://doi.org/10.1080/13510347.2013.738861 Lafi, A., Josserand, E. (2016). Legitimation in practice: A new digital publishing business model. Journal of Business Research, 69(7), 23432352. https://doi.org/10.1016/j.jbusres.2015.10.003 Mackay, R. R. (2015). Multimodal legitimation: Selling Scottish independence. Discourse Society, 26(3), 323348. https://doi.org/10.1177/0957926514564737 ONeil, I., Ucbasaran, D. (2016). Balancing what matters to me with what matters to them: Exploring the legitimation process of environmental entrepreneurs. Journal of Business Venturing, 31(2), 133152. https://doi.org/10.1016/j.jbusvent.2015.12.001 Shirley, D. (2015). The legitimation crisis of educational change. Journal of Educational Change, 16(3), 245250. https://doi.org/10.1007/s10833-015-9254-4 Voronov, M., De Clercq, D., Hinings, C. R. (2013). Conformity and Distinctiveness in a Global Institutional Framework: The Legitimation of Ontario Fine Wine. Journal of Management Studies, 50(4), 607645. https://doi.org/10.1111/joms.12012

Dell Computer Corporation Essays - Lean Manufacturing,

Dell Computer Corporation SYNOPSIS In this report an examination will be made of the production and logistics system of Dell Computer Corporation. Emphasis will be placed on the following: The important aspects of Dells product/ service How effective is the firms resource planning procedures? Dells internal and external logistics process The key difficulties - potential points of failure in the Dells logistics process How technologies are being used or can be used to make the logistics function more efficient/effective? What is Dell Computers all about? Michael Dell founded Dell Computer Corporation in 1984 having only $1000 start-up capital. To date, his business has grown to become the second largest computer systems producer in the world, with average daily sales of more than $5 million. The hub of Dells production system is based in the U.S (Round rock, Texas), while other factories are located in Nashville, Tennessee, Limerick, (Ireland), Penang, Malaysia, Xiamen, China and Eldorado do Sul, Brazil. Dell has offices in thirty-four countries around the world and sells its products and services in more than one hundred and seventy countries. The table below provides a break down of Dells global market growth and position. Monetary values are quoted in US$ in millions. Continent Market Position Net Revenue as at January 28/2000 Annual Growth Rate Dell Americas Dell Europe/Middle East/Africa Dell Asia Pacific and Japan 1 2 7 17879 5590 1796 48% 24% 52% According to Dells forecast it is estimated that total revenue will amount to US$33 billion this year, where US$20 billion will be as a result of online transactions. (1) In the Appendix of this report, a consolidated statement of income on Dells financial position for the year ending 28/1/00 is presented. The important aspects of Dells Product and Service Dells core competency lies in customising its product computer hardware and software to the specific needs of the consumer. The organisation has been able to gain a cost advantage by creating a standardised product as well as achieving the market advantage of variety and uniqueness. The modular design of Dells products has made that possible. Dells use of modular design involves using a standardised building block/chassis to which; value is added by building each product to the customers specifications, the outcome being a unique finished product. Modular design also gives Dell the increased flexibility in its procurement function. The diagram below highlights this flexibility: Dell Computers Corp Suppliers (figure 1.1) Suppliers Figure 1.1 provides a simplistic example of Dells supply chain. The numbered squares each represent a component supplier. Hypothetically speaking lets us assume that supplier number 5 provides Dell with circuit boards. Management has discovered that it would be more efficient ordering that component from a regional supplier, therefore decides to cut supplier 5 out of the supply chain and switches to supplier number 6. The modular design of the product makes that possible as well as the fact that the bulk of the components are not being ordered from a single supplier. Dells product range includes the following: Based on the information above it can be said that, Dell is one of the most ideal models of a market-orientated organisation. By having a direct relationship with its customers the organisation has been able to gain an understanding of their individual needs and therefore, strategically segmenting the market as follows: Home and Home office Small business Center (businesses under 400 employees) Medium and large business (businesses with over 400 employees) Internet Service Providers (Internet service providers, application service providers and web hosting companies) Health Care business Government agencies Education facilities Dell has characterised its relationship with the market segments above under one broad heading that is The Dell Direct Model. The Dell Direct Model This model involves several factors namely: Build to order manufacturing Low cost high speed distribution and procurement system Direct relationship with customers These three factors are essentially the backbone of Dells operations and the means through which the organisation is able to differentiate itself from competitors, therefore sustaining a significant competitive advantage. Dell is the entire distribution channel from the procurement to the delivery of the finished product/service to the consumer. By eliminating the middleman in the supply chain Dell is able to exert greater control over cost and quality in the product and the efficiency of the lead-time. The organisation realises that each of its market

Balustrades, Balusters, and How to Preserve Them

Balustrades, Balusters, and How to Preserve Them A baluster has come to be known as any vertical brace (often a decorative post) between an upper and lower horizontal railing. The purposes of the baluster  (pronounced BAL-us-ter) include safety, support, and beauty. Staircases and porches often have rails of balusters called balustrades.   A balustrade is a row of repeating balusters, similar to a colonnade being a row of columns. What we call a balustrade today is historically a decorative extension of the Classical Greek colonnade on a smaller scale. The invention of the balustrade is generally thought to be a feature of Renaissance architecture. One example is the balustrade of the 16th century Basilica St. Peters at the Vatican. Todays balusters are constructed of wood, stone, concrete, plaster, cast iron or other metal, glass, and plastics. Balusters can be rectangular or turned (i.e., shaped on a lathe). Today any decorative patterned grille or cutout (patterned after the Roman lattice) between railings are referred to as balusters. Balusters as architectural details are found in homes, mansions, and public buildings, inside and outside. The Baluster Shape: Balustrade (pronounced BAL-us-trade) has come to mean any series of vertical bracings between rails, including spindles and simple posts. The word itself reveals a certain design intention. Baluster is really a shape, coming from the Greek and Latin words for a wild pomegranate flower. Pomegranates are ancient fruits indigenous to the Mediterranean, Middle East, India, and Asia, which is why you find the baluster shape in these areas of the world. Having hundreds of seeds, pomegranates also have long been symbols of fertility, so when ancient civilizations decorated their architecture with objects from nature (e.g., the top of a Corinthian column is decorated with acanthus leaves), the shapely baluster was a good decorative choice. What we call the baluster shape was depicted in pottery and jugs and wall carving in many parts of the world from the earliest civilizations- the potters wheel was invented around 3,500 BC, so wheel-turned shapely water jugs and baluster vases were more easily produced- but the baluster was not used in architecture until thousands of years later, during the Renaissance. After the Middle Ages, from roughly 1300 until 1600, a new interest in Classical design was reborn, including the baluster design. Architects like Vignola, Michelangelo, and Palladio incorporated the baluster design into Renaissance architecture, and today balusters and balustrades are considered the architectural detail itself. In fact, our common word banister is a corruption or mispronunciation of baluster. Preservation of Balustrades: Exterior balustrades are obviously more susceptible to decay and deterioration than interior balustrades. Proper design, manufacturing, installation, and regular maintenance are keys to their preservation. The US General Services Administration (GSA) defines balustrade by its components, consisting of the handrail, footrail and balusters. The handrail and footrail are joined at the ends to a column or post.   The balusters are vertical members that connect the rails. Wooden balustrades are subject to deterioration for a number of reasons, including exposed end grain from the manufacturing process and butt joints that are prone to moisture. Regular inspection and maintenance of a well-designed balustrade are the keys to continued care and preservation. A wooden balustrade in proper condition is rigid and free from decay, the GSA reminds us. It is designed with sloping surfaces to repel water and has properly caulked, tight joints. Exterior cast stone (i.e., concrete) balusters will have moisture problems if not designed and installed properly and if not routinely inspected. Balusters come in many shapes and sizes, and the quality of construction and thickness of the balusters neck may affect its integrity. The variables involved in manufacture are considerable, and it is wise to use a firm with experience in ornamental and custom work rather than a precast concrete firm which manufactures stock structural items, suggests preservationist Richard Pieper. The Case for Preservation: So, why preserve balustrades in public buildings or on your own home? Why not just cover them up, encase them in metal or plastic and protect them from environmental hazards? Balustrades and railings are not only practical and safety features, write preservationist John Leeke and architectural historian Aleca Sullivan, they typically are highly visible decorative elements. Unfortunately, balustrades and balusters are frequently altered, covered, removed or completely replaced even though in most cases they can be repaired in a cost-effective manner. Routine cleaning, patching, and painting will preserve all kinds of balustrades. Replacement should be a last resort only. To preserve historic fabric, the repair of old balustrades and railings is always the preferred approach, Leeke and Sullivan remind us. A broken baluster usually is one in need of repair, not replacement. Sources: Baluster, Illustrated Architecture Dictionary, Buffalo Architecture and History; Classical Comments: Balusters by Calder Loth, Senior Architectural Historian for the Virginia Department of Historic Resources; Securing An Exterior Wooden Balustrade, U.S. General Services Administration, November 5, 2014; Removing And Replacing Deteriorated Cast Stone Balusters, U.S. General Services Administration, December 23, 2014; Preserving Historic Wood Porches by Aleca Sullivan and John Leeke, National Park Service, October 2006; The Maintenance, Repair and Replacement of Historic Cast Stone by Richard Pieper, National Park Service, September 2001 [accessed December 18, 2016]

Case study of Business strategy Essay Example | Topics and Well Written Essays - 2750 words

Case study of Business strategy - Essay Example e origins of CEMEX was traced in 1906 as Cementos Hidalgo and eventually merged with Cementos Portland Monterrey to form the Cementos Mexicanos, later renamed CEMEX, with Lorenzo Zambrano as its founder. The Lorenzo Zambrano, appointed as the CEO of contemporary CEMEX, was a direct descendant and namesake of the original founder. From the strategies employed and implemented by Zambrano, the most critical was refocusing from the horizontal diversification to a strategy of geographic diversification within the cement business with the objective of attaining growth through acquisitions (Bartlett, Ghoshal & Beamish, 2008, p. 251). This defined Zambrano’s vision to make CEMEX an emerging global giant entrenched as a leader in the cement production and marketing. CEMEX slowly developed its competitive advantage in the cement industry by gaining expertise with priority in its homeland, Mexico. By investing in a$1 billion merger through the acquisition of significant cement producers in Mexico (Cementos Anahuac and Cementos Tolteca); CEMEX was able to secure the market leader position in Mexico, a move which proved to be an effective strategy prior to focusing in geographic diversification through purchase of cement companies in selected international markets. As averred by Ghemawat & Hout (2008), there are basically three significant strategies employed by global giants of the future, to wit: (1) exploiting evolving market conditions; (2) managing convergences in costs; and (3) reworking value chains (pp. 82 – 87). CEMEX has been effective in exploiting evolving market conditions. Through the challenges met from its stance to dominate the Mexican market, despite the peso crisis and the political instability that marked years of operating in their local market, CEMEX managed to generate profit margins partly due to servicing the self-construction part which was minimally affected by the crunch. Further, during the period, CEMEX has already started to venture into

Aristotle's Theory Essay Example | Topics and Well Written Essays - 250 words

Aristotle's Theory - Essay Example e fact that Aristotle believes that the soul exists until there is a body, the philosopher recognizes activity of the mental processes and their involvement in physiological states of a person. Considering the relationship between body and soul, Aristotle points out an inextricable link between them. â€Å"Unlike Plato, he has no objection to so intimate a relation between the mental and the physical† (Caston 331). In fact, he expresses the conviction that their interaction can be regarded as monism. Recognizing the link between body and soul, Aristotle says that the soul is active, not passive. Unlike the supporters of epiphenomenalism, Aristotle argues that the physiological processes can be the result of certain psychological processes. There are two possibilities (Caston 330). Some physiological processes are the result of both physical and psychological conditions, while others can only be the result of certain mental changes. To sum up, there are no reasons to believe that Aristotle supports the standpoint of epiphenomenalism on the importance of psychological states in human activities. On the contrary, Aristotle emphasizes activity of the mental properties and their impact on various physiological states. Thus, Aristotle understands the unity of body and soul as an opportunity to influence each

Relationship between Terrorism and Religion Essay

Relationship between Terrorism and Religion - Essay Example Principally, this ideologically has driven our world since the twentieth century, and it is now making way to the twenty-first century. Also, now it appears to have settled in people in a more ‘religious accommodating’ manner. The final years of the twentieth century, in fact, already underwent an exceptional resurgence of historical religions in numerous parts of the globe, comprising the former USSR, Eastern/Central Europe, as well as China. It is not restricted to only the rebirth of historical religions or faiths, but also extended to the surfacing of neo-religious groups such as the New Age spirituality, as well as the surge of faithfully based experiences and practices ranging from medicine to meditation. These movements have made their way into societies and communities all through the globe where definite levels of freedom for spiritual and religious groups are present. Religious values and views play a significant role in the lives of individuals as they cope wi th issues affecting their communities. Religions educate people concerning ultimate views on believers’ lives. They also offer a core vision for people’s lives, which habitually shades its followers’ socio-political hopes, behaviors and engagements. Therefore, the significance of religion to terrorism cannot be overlooked. This paper will focus on the relationship between terrorism and religion based on what these three authors say in their writings: Brigitte Nacos, Martha Crenshaw and Richard Connerney. These articles are â€Å"The Making of Terrorists: Causes, Conditions, Influences;† â€Å"The Logic of Terrorism;† and â€Å"Islam† respectively.... The author also touches on the new-fangled and past/historical trends of terrorism. Extensively discussing the subject â€Å"What is terrorism?,† the author, a celebrated expert in this field, visibly discusses and explains terrorism’s numerous causes, strategies and actors, as well as counter- and anti-terrorist responses. This article, in addition, outstandingly examines terrorism’s relationship with religion, the public and the media. Highly readable and also comprehensive, â€Å"The Making of Terrorists: Causes, Conditions, Influences† introduces the readers to significant concepts and theories in the study of terrorism with its relation to religion and political turmoil. It also helps them challenge presumptions of this vital, as well as complex issue. Any macro level matter, according to Nacos (61), cannot be tackled without being receptive to realities of religion experienced by humans. Whether the hope of humanity will be formed by the ‘clash of ignorance,’ the ‘clash of societies,’ the clash of religions/faiths and traditions, or conflicts between the ‘West and the rest’ is difficult to predict. It might be an amalgamation of a number of the above because they are all intricately related (Nacos 61). Also, it might be caused by the surfacing of previously unclear issues or problems of polarization. Nacos gives the instance of the 9/11 attacks where Muslim terrorists from the Middle East decided to attack the famous American Twin Towers. In the past, there has always been a religious conflict between the people of the Middle East and the Americans. This was the main reason that according to Nacos (62) led to the bombing of the American Twin Towers. Therefore, Nacos concluded in her article that a